How is ZYRTEC-D® different from ZYRTEC®?

ZYRTEC-D® contains pseudoephedrine, which relieves nasal congestion. So it relieves all the same symptoms as ZYRTEC®, plus it also has a powerful decongestant. For more, see:

How does ZYRTEC-D® work on sinus pressure and congestion?

ZYRTEC-D® contains a nasal decongestant that narrows the blood vessels in the nose and sinus region, which shrinks the tissue in that area to allow air and mucus to flow normally.

Why is ZYRTEC-D® located behind the pharmacy counter?

Pseudoephedrine, an active ingredient in some cold, allergy, and sinus products, can be chemically processed into methamphetamine (commonly known as meth). The illegal use of meth had increased, prompting Congress to pass the Combat Methamphetamine Epidemic Act of 2006 (CEMA). The objective of the law is to eliminate the use of pseudoephedrine in the illegal production of meth. By law, products containing pseudoephedrine must now be sold behind the counter and through online retailers who must meet certain requirements. Note that products containing pseudoephedrine remain available without a prescription in most states.

Why does the product look different?

We have developed new outer packaging to support Kenvue’s commitment to innovation and sustainability through their Healthy Lives Mission. The 100% paper carton is recyclable and features a modern, flat-front design with improved readability.

Will the product work differently?

No, the product contains the same ingredients that helps relieve kids’ indoor and outdoor allergy symptoms such as runny nose, sneezing, and itchy nose and throat for a full 24 hours.

Will the product’s dosage or quantity change with the new packaging?

No, the formula has not changed, and the dosage and quantity has not changed.

Allergy relief & nasal decongestant 12 count front pack image

ZYRTEC-D®: Allergy relief & nasal decongestant in one & starts to work on congestion in 30 minutes.

FAST relief of symptoms that may be triggered by 200+ allergens including pollen, pet dander, dust

Green background and text "24-hour relief of" graphics: runny nose, sneezing, itchy eyes/nose/throat

ZYRTEC®-D starts to work on congestion in 30 minutes

Graphic of HSA/FSA eligibility claim, no prescription needed*

ZYRTEC-D®: Allergy relief & nasal decongestant back pack image

ZYRTEC-D^® Allergy + Congestion Relief Tablets with Decongestant and Cetirizine HCl

Name: ZYRTEC-D® Allergy + Congestion Relief Tablets with Decongestant and Cetirizine HCl
SKU: 000000000302042700
Rating: 4.8 (537 reviews)

USE PRODUCT ONLY AS DIRECTED

SIZE

The proven allergy relief of ZYRTEC^® plus a decongestant to provide powerful allergy congestion relief. ZYRTEC-D^® Allergy Relief and Nasal Decongestant Tablets contain 5 mg cetirizine HCl antihistamine and 120 mg pseudoephedrine decongestant for relief from nasal congestion, sinus pressure, and allergy symptoms caused by pollen, dust, pet dander, mold, and other airborne allergens. These 2-in-1 allergy medicine tablets get to work in as little as 30 minutes, for allergy congestion relief that lasts for 12 hours.

From the #1 doctor and allergist recommended OTC allergy brand when it comes to oral antihistamines, this extended-release 12 hour allergy medicine plus decongestant is suitable for those 12 years of age and older.

There are current regulations that apply to the sale of pseudoephedrine products, so ZYRTEC-D^® can only be sold in stores behind the pharmacist counter. It is not available for online purchase. No prescription needed.*

_{*In most states.}

Allergy relief & nasal decongestant tablets
5 mg cetirizine HCl & 120 mg pseudoephedrine
For sinus pressure & nasal congestion relief

This website contains current product information and may differ from the information on the product packaging you may have. If you have any questions, please contact the Consumer Care Center (CCC) at 1-800-343-7805

Caring for Your Allergies

Starts working in 30 minutes

Allergy relief + nasal decongestant

12-hour allergy relief

Zyrtec Relief from 200+ different allergens icon

Allergy relief from 200+ different allergens

Caring for the Planet

Outer packaging 100% plastic-free

Outer packaging made of 100% recyclable paper

Active Ingredient

Cetirizine HCl 5 mg (in each extended release tablet)

Pseudoephedrine HCl 120 mg (in each extended release tablet)

When you have an allergic reaction, your immune system releases chemicals called histamines to fight the allergen, which leads to various allergy symptoms. Cetirizine helps relieve these allergy symptoms by blocking the effects of histamines, reducing the severity of your symptoms.

See all ZYRTEC® ingredients